Mysimba
(Naltrexon 8mg /90mg Bupropion)
This medication cannot be delivered to a UK resident.
This medication is not dispensed from a UK pharmacy
Medication Dosage Quantity Price Proceed to consultation
Mysimba® Naltrexon 8mg /
90mg Bupropion112 Tablets €219,00
Proceed to consultation
Mysimba® Naltrexon 8mg /
90mg Bupropion224 Tablets €369,00 Proceed to consultation
Mysimba® Naltrexon 8mg /
90mg Bupropion336 Tablets €499,00
Proceed to consultation
What is Mysimba used for?
Mysimba is a medicine used along with diet and exercise to help manage weight in adults:
- who are obese (have a body-mass index – BMI – of 30 or more);
- who are overweight (have a BMI between 27 and 30) and have weight-related complications such as diabetes, abnormally high levels of fat in the blood, or high blood pressure.
BMI is a measurement that indicates body weight relative to height.
How is Mysimba used?
Mysimba contains the active substances naltrexone and bupropion, which are licensed individually in the EU for other uses.
Mysimba is available as prolonged-release tablets containing 7.2 mg naltrexone and 78 mg bupropion and can only be obtained with a prescription. Prolonged release means that naltrexone and bupropion are released slowly from the tablet over a few hours.
Treatment with Mysimba is started with a single tablet each morning, with the dose gradually increased over 4 weeks to the recommended dose of two tablets twice a day, preferably taken with food.
Patients should have their response and tolerability to the medicine checked regularly and treatment should be stopped in patients who have certain side effects such as an increase in blood pressure. Mysimba should also be stopped if patients have not lost at least 5% of their initial body weight after 4 months of treatment.
How does Mysimba work?
The exact way that Mysimba works is not fully understood, but the two active substances, naltrexone, and bupropion, act on the parts of the brain that control food intake and energy balance, as well as reducing the effect of the part of the brain that controls the pleasure associated with eating food. When given together, their actions reduce appetite and the amount that patients eat, and increase energy expenditure, helping them to stick to a calorie-controlled diet and to reduce their body weight.
Risks associated with Mysimba
The most common side effects of Mysimba (which may affect more than 1 in 10 people) are nausea and vomiting (feeling and being sick) and constipation; dizziness and dry mouth were also common (seen in up to 1 patient in 10).
Mysimba must not be used in certain patients at particular risk of side effects, including patients with severely reduced kidney or liver function, those with high blood pressure that is not under control, those who have ever had seizures (fits), certain psychological problems or who have a brain tumor or are undergoing withdrawal from alcohol or certain drugs.
